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Creative Enzymes Launched Tn5 Transposase for Genetic Experimentation

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Creative Enzymes Launched Tn5 Transposase for Genetic Experimentation

April 09
23:06 2021
Creative Enzymes has recently launched Tn5 Transposase for researchers. With more than ten-year experience in offering professional services and high-quality products for academic use and pharmaceutical industries, Creative Enzymes is able to offer remarkable enzymes related services for the enzymes market.

New York, USA – April 9, 2021 – Creative Enzymes, a professional enzyme provider located in New York, always hammers at researches and trials in order to provide customers with various enzyme products and services as many as possible. Creative Enzymes has recently launched Tn5 Transposase for researchers. With more than ten-year experience in offering professional services and high-quality products for academic use and pharmaceutical industries, Creative Enzymes is able to offer remarkable enzymes related services for the enzymes market.

Transposase is an enzyme that binds to the end of a transposon and catalyzes its movement to another part of the genome by a cut and pastes mechanism or a replicative transposition mechanism. Genes encoding transposases are widespread the most abundant in the genomes of most organisms and are the most abundant genes known.

Transposase (Tnp) Tn5 is a member of the RNase superfamily of proteins which includes retroviral integrases. Tn5 can be found in Shewanella and Escherichia bacteria. The transposon codes for antibiotic resistance to kanamycin and other aminoglycoside antibiotics. Transposition works through a “cut-and-paste” mechanism, where the Tn5 excises itself from the donor DNA and inserts into a target sequence, creating a 9-bp duplication of the target.

DNA transposition is a useful model that can be used to understand the interaction of other types of proteins with DNA. For example, retroviral DNA integration and DNA cleavage events involved in the formation of immunoglobulin genes, and because Tn5-derived tools are useful auxiliary tools in genetic experiments. In addition, in a technology called ATAC-seq, Tn5 is used for genome sequencing to fragment DNA. A major advancement in library preparation is the introduction of a highly active variant of Tn5 transposase, which mediates the fragmentation of double-stranded DNA and ligates synthetic oligonucleotides to both ends in a 5-minute reaction.

“Creative Enzymes has developed Tn5 transposase that can meet different types of research needs. With decades of experience and unique technology, we are committed to providing customers with the highest quality enzyme products.” stated Creative Enzymes’s executive vice president.

What are the applications of Tn5 transposase?

• The study of Tnp Tn5 is important because of its similarity to HIV-1 and other retroviral diseases.
• By studying Tn5, more about other transposases and their activities can also be discovered.
• Tn5 is utilized in genome sequencing for fragmentation of the DNA, in the technique called ATAC-seq and also in Illumina dye sequencing.

“Creative Enzymes has a professional research and development team of enzyme products. Team members have a high level of expertise and rich experience. Therefore, we can provide customers with comprehensive, professional, and one-stop solutions. Please feel free to contact us if you have any questions about our services and products.” Said the product manager of Creative Enzymes.

About Creative Enzymes

Creative Enzymes is a remarkable supplier and manufacturer in Enzymology field. Equipped with an advanced technique platform, Creative Enzymes is able to offer high-quality and professional services for customers. Its products and services are widely used in the academic and pharmaceutical industries.

Media Contact
Company Name: Creative Enzymes
Contact Person: Iva Colter
Email: Send Email
Phone: 1-516-855-7709
Country: United States
Website: https://www.creative-enzymes.com


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